SCHEMBL6156979

SCHEMBL6156979

C=CC(=O)OCC(O)OC

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.61
HPGD P15428 1/20 0.44
ALDH1A1 P00352 5/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 3/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
THRB P10828 3/20 0.37
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431912 0.81 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28632742 0.81 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18123454 0.81 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
Methoxymethane SCHEMBL5167315 0.81 TSHR (0.69) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27821519 0.80
SCHEMBL27800525 0.80
SCHEMBL33585 0.80
SCHEMBL7116239 0.80 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28450987 0.80 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL268127 0.79 TSHR (0.73) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1001309-B1 Silver halide photographic light sensitive material and image forming method using thereof KONISHIROKU PHOTO IND (JP) 2005-01-19 EP disclosed
US-6183945-B1 COLOR FASTNESS; STABILITY OF IMAGE; STORAGE STABILITY; ADAPTABILITY TO RAPID PHOTOPROCESSING KONICA CORPORATION (JP) 2001-02-06 US disclosed
US-5925506-A HAVING THE FLUORESCENT WHITENING AGENT-CONTAINING LAYER POSITIONED BETWEEN THE SUPPORT AND ULTRAVIOLET ABSORBENT-CONTAINING LAYER; TWO LAYERS CONTAINING THE WHITENING AGENT-CAPTURING COMPOUND STRATEGICALLY POSITIONED; ANTISOILANTS KONICA CORPORATION (JP) 1999-07-20 US disclosed