Indole

Indole

SCHEMBL6157061

c1ccc2[nH]ccc2c1.c1ccoc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.74
CA1 P00915 2/20 0.74
CA4 P22748 2/20 0.74
CA6 P23280 2/20 0.74
TRPA1 O75762 1/20 0.74
CA2 P00918 1/20 0.74
ITGB2 P05107 1/20 0.74
ICAM1 P05362 1/20 0.74
ITGAL P20701 1/20 0.74
ADK P55263 1/20 0.74
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.39
NR4A2 P43354 2/20 0.38
CYP2A6 P11509 2/20 0.38
CMA1 P23946 1/20 0.38
F7 P08709 1/20 0.38
LTA4H P09960 1/20 0.38
F3 P13726 1/20 0.38
PARP1 P09874 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL28071644 0.86 AHR (1.00) AHRCA1CA4CA6TRPA1
Indole SCHEMBL29352896 0.86
Indole SCHEMBL30250492 0.86
Indole SCHEMBL30463845 0.86
Indole SCHEMBL698 0.86
Indole SCHEMBL1160186 0.86 AHR (1.00) AHRCA1CA4CA6TRPA1
Indole SCHEMBL23886438 0.84 AHR (0.94) AHRCA1CA4CA6TRPA1
Indole SCHEMBL2346637 0.84 AHR (0.94) AHRCA1CA4CA6TRPA1
Indole SCHEMBL2000860 0.84 AHR (0.94) AHRCA1CA4CA6TRPA1
Indole SCHEMBL1475229 0.84 AHR (0.94) AHRCA1CA4CA6TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118056830-A Axis chiral indolopyrrole-furan compound and synthesis method thereof 江苏师范大学 2024-05-21 CN claimed
CN-100361990-C Second order non-linear optical chromophore containing indolyl radical and its prepn and application UNIV WUHAN (CN) 2008-01-16 CN claimed
CN-1740171-A Second order non-linear optical chromophore containing indolyl radical and its prepn and application UNIV WUHAN (CN) 2006-03-01 CN claimed
US-6403835-B1 Acylation of an organic group over a zeolite CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-06-11 US claimed
WO-2001032593-A1 ACYLATION OF AN ORGANIC GROUP OVER A ZEOLITE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-05-10 WO claimed
CN-118056830-A Axis chiral indolopyrrole-furan compound and synthesis method thereof 江苏师范大学 2024-05-21 CN disclosed
CN-100361990-C Second order non-linear optical chromophore containing indolyl radical and its prepn and application UNIV WUHAN (CN) 2008-01-16 CN disclosed
CN-1740171-A Second order non-linear optical chromophore containing indolyl radical and its prepn and application UNIV WUHAN (CN) 2006-03-01 CN disclosed
EP-1481014-A4 POLY(HETEROAROMATIC) BLOCK COPOLYMERS WITH ELECTRICAL CONDUCTIVITY TDA RESEARCH INC (US) 2005-08-03 EP disclosed
EP-1481014-A1 POLY(HETEROAROMATIC) BLOCK COPOLYMERS WITH ELECTRICAL CONDUCTIVITY TDA RESEARCH, INC. (US) 2004-12-01 EP disclosed
WO-2003018648-A1 POLY(HETEROAROMATIC) BLOCK COPOLYMERS WITH ELECTRICAL CONDUCTIVITY TDA RESEARCH, INC. (US) 2003-03-06 WO disclosed