Sugi Predict

Sugi Predict / Compounds / SCHEMBL6157495

SCHEMBL6157495

SCHEMBL6157495

CCCCCCCC(C)CCC(C)COS(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACE2 Q9BYF1 1/20 0.51
▸ TP53 P04637 1/20 0.46
▸ PRKD3 O94806 1/20 0.39
▸ PRKCG P05129 1/20 0.39
▸ PRKCB P05771 1/20 0.39
▸ PRKCA P17252 1/20 0.39
▸ PRKCH P24723 1/20 0.39
▸ PRKCI P41743 1/20 0.39
▸ PRKCE Q02156 1/20 0.39
▸ PRKCQ Q04759 1/20 0.39
▸ PRKCZ Q05513 1/20 0.39
▸ PRKCD Q05655 1/20 0.39
▸ PRKD1 Q15139 1/20 0.39
▸ SMPD1 P17405 3/20 0.36
▸ CA1 P00915 6/20 0.35
▸ CA2 P00918 6/20 0.35
▸ CA9 Q16790 6/20 0.35
▸ FDPS P14324 3/20 0.35
▸ GPR84 Q9NQS5 2/20 0.35
▸ CA12 O43570 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026574 1.00 ACE2 (0.51) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL6157250 1.00 ACE2 (0.51) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL4611652 1.00 ACE2 (0.51) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL7023351 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL4772926 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL4772596 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL7031451 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL4780155 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL4773928 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB
SCHEMBL7024500 0.98 ACE2 (0.49) ACE2TP53PRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10975056-B2 Substituted pyridines as inhibitors of DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2021-04-13 — — US disclosed
US-10975056-B2 Substituted pyridines as inhibitors of DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2021-04-13 — — US disclosed
US-20190194166-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-06-27 — — US disclosed
US-20190194166-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-06-27 — — US disclosed
EP-3468953-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GlaxoSmithKline Intellectual Property Development Limited (GB) 2019-04-17 — — EP disclosed
WO-2017216726-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-12-21 — — WO disclosed
WO-2017216727-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-12-21 — — WO disclosed
WO-2017216726-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-12-21 — — WO disclosed
WO-2017216727-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-12-21 — — WO disclosed
US-6924300-B2 Oxyiminoalkanoic acid derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 — — US disclosed
WO-1999018929-A9 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS PROCTER & GAMBLE (US) 1999-08-26 — — WO disclosed
WO-1999019449-A1 HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019440-A1 LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019439-A1 LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019448-A1 HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019450-A1 AQUEOUS AND NON-AQUEOUS HEAVY DUTY LIQUID DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019434-A1 GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999019435-A1 GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999018929-A1 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed
WO-1999018928-A1 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10975056-B2 Substituted pyridines as inhibitors of DNMT1 DNMT1, DNMT3A, DNMT3B ACE2 4022/4885TP53 435/4885PRKD3 1923/4885
US-20190194166-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 DNMT1, DNMT3A, DNMT3B ACE2 4022/4885TP53 435/4885PRKD3 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.