Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786621 | 0.98 | SPHK1 (0.61) | SPHK1OPRM1CYP2D6TP53GMNN | |
| SCHEMBL8369324 | 0.98 | SPHK1 (0.61) | SPHK1OPRM1CYP2D6TP53GMNN | |
| SCHEMBL4891618 | 0.98 | SPHK1 (0.61) | SPHK1OPRM1CYP2D6TP53GMNN | |
| SCHEMBL460570 | 0.98 | SPHK1 (0.61) | SPHK1OPRM1CYP2D6TP53GMNN | |
| SCHEMBL1742708 | 0.98 | SPHK1 (0.61) | SPHK1OPRM1CYP2D6TP53GMNN | |
| Hydrochloric Acid SCHEMBL11187511 | 0.95 | SPHK1 (0.59) | SPHK1OPRM1CYP2D6TP53GMNN | |
| Hydrochloric Acid SCHEMBL11461378 | 0.95 | SPHK1 (0.59) | SPHK1OPRM1CYP2D6TP53GMNN | |
| SCHEMBL18923235 | 0.92 | — | — | |
| SCHEMBL18109577 | 0.92 | — | — | |
| SCHEMBL15241781 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116709-A1 | Process for producing optically active n-aryl-1-amino-2-propanol derivatives | KANEKA CORPORATION (JP) | 2004-06-17 | — | — | US | claimed |
| EP-1367053-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE N-ARYL-1-AMINO-2-PROPANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2003-12-03 | — | — | EP | claimed |
| WO-2014059593-A1 | POLYURETHANE BASED SYNTHETIC LEATHERS COMPRISING NANOPARTICLES AND HAVING IMPROVED PEEL STRENGTH | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-1367053-A4 | PROCESS FOR PRODUCING OPTICALLY ACTIVE N-ARYL-1-AMINO-2-PROPANOL DERIVATIVES | KANEKA CORP (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20040116709-A1 | Process for producing optically active n-aryl-1-amino-2-propanol derivatives | KANEKA CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20040116709-A1 | Process for producing optically active n-aryl-1-amino-2-propanol derivatives | KANEKA CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20040116709-A1 | Process for producing optically active n-aryl-1-amino-2-propanol derivatives | KANEKA CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1367053-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE N-ARYL-1-AMINO-2-PROPANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-1367053-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE N-ARYL-1-AMINO-2-PROPANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002070482-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE N-ARYL-1-AMINO-2-PROPANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2002-09-12 | — | — | WO | disclosed |
| EP-0325977-A1 | Phosphite amine lubricant additives | THE ELCO CORPORATION (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4758547-A | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4602089-A | Process for preparing purine compounds | NEWPORT PHARMACEUTICALS, INC. (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0126813-A1 | Process for preparing imidazole compounds | Newport Pharmaceuticals International, Inc. (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4451478-A | IMMUNOLOGY, ACTIVATORS | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1984-05-29 | — | — | US | disclosed |