Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584891 | 0.88 | HTR2C (0.59) | MEN1KMT2AHTR2CCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6197567 | 0.83 | HTR2C (0.56) | MEN1KMT2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL6160494 | 0.82 | SLC6A2 (0.53) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6872023 | 0.76 | PROKR1 (0.44) | MEN1KMT2AHTR2CCHRNB2CHRNA4 | |
| SCHEMBL2707057 | 0.75 | HTR2C (0.63) | MEN1KMT2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL13614313 | 0.75 | OPRL1 (0.38) | CHRNB2CHRNA4ABL1ABCB1BCR | |
| SCHEMBL5534626 | 0.74 | HTR2C (0.61) | HTR2CCHRNB2CHRNA4SLC6A2SLC6A4 | |
| SCHEMBL1529068 | 0.74 | HTR2C (0.58) | MEN1KMT2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL22324792 | 0.74 | HTR2C (0.58) | MEN1KMT2AHTR2CCHRNB2CHRNA4 | |
| SCHEMBL24954120 | 0.73 | HTR2C (0.56) | MEN1KMT2AHTR2CSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |