Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158330 | 1.00 | HPGD (0.49) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6158326 | 1.00 | HPGD (0.49) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6158859 | 0.90 | HPGD (0.43) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6158788 | 0.90 | HPGD (0.47) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6157836 | 0.89 | TSHR (0.42) | HPGDTSHRHCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL6157901 | 0.87 | HCRTR1 (0.44) | HPGDTSHRHCRTR1HCRTR2CNR2 | |
| SCHEMBL6157459 | 0.86 | SMN1; SMN2 (0.43) | TSHRHCRTR1HCRTR2SMN1; SMN2KMT2A | |
| SCHEMBL6160144 | 0.85 | SMN1; SMN2 (0.45) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6158423 | 0.85 | SMN1; SMN2 (0.45) | HPGDTSHRHCRTR1HCRTR2HTT | |
| SCHEMBL6157442 | 0.85 | HCRTR1 (0.46) | HPGDTSHRHCRTR1HCRTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953789-B2 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-10-11 | — | — | US | disclosed |