Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158757 | 0.90 | EGLN1 (0.49) | HCRTR1HCRTR2EGLN1HDAC1HDAC6 | |
| SCHEMBL6159505 | 0.88 | HDAC1 (0.51) | HCRTR1HCRTR2HDAC1HDAC6HRH3 | |
| SCHEMBL6160370 | 0.85 | HCRTR1 (0.51) | HCRTR1HCRTR2FFAR1EGLN1HDAC1 | |
| SCHEMBL6158510 | 0.84 | HCRTR1 (0.52) | HCRTR1HCRTR2EGLN1HDAC1HDAC6 | |
| SCHEMBL6157202 | 0.83 | HCRTR1 (0.53) | HCRTR1HCRTR2FFAR1EGLN1HDAC1 | |
| SCHEMBL6158664 | 0.82 | HCRTR1 (0.48) | HCRTR1HCRTR2EGLN1HDAC1HDAC6 | |
| SCHEMBL6162062 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL6159092 | 0.81 | HCRTR1 (0.51) | HCRTR1HCRTR2FFAR1EGLN1HDAC1 | |
| SCHEMBL6159008 | 0.80 | HCRTR1 (0.55) | HCRTR1HCRTR2FFAR1EGLN1HDAC1 | |
| SCHEMBL6160316 | 0.80 | HCRTR2 (0.53) | HCRTR1HCRTR2HDAC1HDAC6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953789-B2 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-10-11 | — | — | US | disclosed |
| US-6420415-B1 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |