SCHEMBL6159634

SCHEMBL6159634

Cc1ccc(-c2cc(C#N)c(OCCc3ccc(F)cc3)nc2-c2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.75
CNR2 P34972 10/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162315 0.94 CNR1 (0.83) CNR1CNR2
SCHEMBL5355026 0.85 CNR1 (1.00) CNR1CNR2
SCHEMBL5354934 0.85 CNR1 (1.00) CNR1CNR2
SCHEMBL5358712 0.85 CNR1 (0.69) CNR1CNR2
SCHEMBL5365315 0.85 CNR1 (1.00) CNR1CNR2
SCHEMBL5358105 0.83 CNR1 (1.00) CNR1CNR2
SCHEMBL5365530 0.82 CNR1 (0.65) CNR1CNR2
SCHEMBL5360355 0.81 CNR1 (0.67) CNR1CNR2
SCHEMBL5358093 0.81 CNR1 (0.84) CNR1CNR2
SCHEMBL5358276 0.81 CNR1 (0.89) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1492784-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES Merck & Co., Inc. (US) 2005-01-05 EP claimed
WO-2003082191-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES MERCK & CO., INC. (US) 2003-10-09 WO claimed
EP-1492784-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES Merck & Co., Inc. (US) 2005-01-05 EP disclosed
WO-2003082191-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES MERCK & CO., INC. (US) 2003-10-09 WO disclosed