Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606281 | 0.87 | KMT2A (0.54) | KMT2AKDM4EGLATDP1L3MBTL1 | |
| SCHEMBL3779398 | 0.85 | KMT2A (0.52) | KMT2AKDM4EGLATDP1L3MBTL1 | |
| SCHEMBL13627962 | 0.82 | KMT2A (0.44) | KMT2AKDM4EGLACHRM5MAPT | |
| SCHEMBL31268670 | 0.80 | TDP1 (0.48) | KMT2AKDM4EGLATDP1L3MBTL1 | |
| SCHEMBL18745560 | 0.80 | MAPT (0.46) | KMT2ATDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL14321903 | 0.80 | PRMT5 (0.48) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL783445 | 0.78 | GLA (0.55) | KMT2AKDM4EGLAMAPTMEN1 | |
| SCHEMBL14321648 | 0.77 | HTT (0.43) | KMT2AKDM4EMAPTMEN1POLB | |
| SCHEMBL783555 | 0.77 | KMT2A (0.48) | KMT2AKDM4EGLATDP1L3MBTL1 | |
| SCHEMBL16711760 | 0.76 | HPGD (0.50) | KMT2AGLAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204322-B1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6630495-B1 | Compound containing 2-pyridyl or its N-oxide | BAYER CROPSCIENCE GMBH (DE) | 2003-10-07 | — | — | US | disclosed |