Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.61 |
| ▸ | ITGAL | P20701 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162223 | 1.00 | MEN1 (0.73) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL19203559 | 0.89 | MEN1 (0.61) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL27885201 | 0.85 | ITGB2 (0.61) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL27885198 | 0.85 | ITGB2 (0.61) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL31606500 | 0.84 | ITGB2 (0.62) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL31036081 | 0.84 | ITGB2 (0.71) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL6164202 | 0.83 | MEN1 (0.58) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6164208 | 0.83 | MEN1 (0.58) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6161756 | 0.83 | CALCRL (0.67) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL8409714 | 0.83 | CALCRL (0.67) | MEN1KMT2AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721455-B9 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2005-04-20 | — | — | EP | claimed |
| EP-0721455-B1 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2002-12-11 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |