Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160835 | 0.95 | DRD4 (1.00) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6162010 | 0.87 | DRD4 (0.88) | DRD4 | |
| SCHEMBL6162118 | 0.85 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6160748 | 0.85 | DRD4 (1.00) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6160267 | 0.83 | DRD4 (0.88) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6161304 | 0.83 | DRD4 (0.88) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6162619 | 0.83 | DRD4 (0.88) | DRD4DRD2 | |
| SCHEMBL6161124 | 0.82 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6164051 | 0.81 | DRD4 (1.00) | DRD4 | |
| Oxalic Acid SCHEMBL6165259 | 0.80 | DRD4 (0.88) | DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920423-B1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH AS (DK) | 2005-01-26 | — | — | EP | disclosed |
| US-6479491-B1 | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, ESPECIALLY PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA | NEUROSEARCH A/S (DK) | 2002-11-12 | — | — | US | disclosed |
| US-6207662-B1 | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA | NEUROSEARCH A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| EP-0920423-A1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH A/S (DK) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007710-A1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH A/S (DK) | 1998-02-26 | — | — | WO | disclosed |