Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168625 | 1.00 | HPGD (0.33) | HPGDMAPTTLR7TLR8GSK3B | |
| SCHEMBL6162355 | 1.00 | HPGD (0.33) | HPGDMAPTTLR7TLR8GSK3B | |
| SCHEMBL8009850 | 1.00 | HPGD (0.33) | HPGDMAPTTLR7TLR8GSK3B | |
| SCHEMBL6162169 | 1.00 | HPGD (0.33) | HPGDMAPTTLR7TLR8GSK3B | |
| SCHEMBL6166944 | 1.00 | HPGD (0.33) | HPGDMAPTTLR7TLR8GSK3B | |
| SCHEMBL6160389 | 0.96 | LPAR3 (0.38) | LPAR3LPAR1 | |
| SCHEMBL6160375 | 0.96 | LPAR3 (0.38) | LPAR3LPAR1 | |
| SCHEMBL6159794 | 0.92 | PPARG (0.33) | HPGD | |
| SCHEMBL6161870 | 0.92 | PPARG (0.33) | HPGD | |
| SCHEMBL6160633 | 0.92 | PPARG (0.33) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |