Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.78 |
| ▸ | CDK4 | P11802 | 11/20 | 0.75 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.75 |
| ▸ | CDK9 | P50750 | 4/20 | 0.75 |
| ▸ | ABL1 | P00519 | 4/20 | 0.75 |
| ▸ | CDK1 | P06493 | 2/20 | 0.75 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.75 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.75 |
| ▸ | CDK7 | P50613 | 2/20 | 0.75 |
| ▸ | CCNH | P51946 | 2/20 | 0.75 |
| ▸ | AURKA | O14965 | 1/20 | 0.75 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.75 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.75 |
| ▸ | CCND1 | P24385 | 1/20 | 0.75 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.75 |
| ▸ | ABL2 | P42684 | 1/20 | 0.75 |
| ▸ | GSK3B | P49841 | 1/20 | 0.75 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.75 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.75 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156443 | 0.88 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL29354713 | 0.88 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL1368256 | 0.86 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL4615663 | 0.86 | CDK2 (0.81) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL29644994 | 0.86 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL2282051 | 0.85 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL4616130 | 0.85 | CDK2 (0.80) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL4803955 | 0.84 | CDK2 (1.00) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL2289217 | 0.84 | CDK2 (0.74) | CDK2CDK4CCNT1CDK9ABL1 | |
| SCHEMBL2288580 | 0.83 | CDK2 (0.77) | CDK2CDK4CCNT1CDK9ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581231-A1 | ANTI-VIRAL COMPOUNDS | Cyclacel Limited (GB) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004043467-A1 | ANTI-VIRAL COMPOUNDS | CYCLACEL LIMITED (GB) | 2004-05-27 | — | — | WO | disclosed |