Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.52 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 3/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161281 | 1.00 | P2RY12 (0.52) | P2RY12CALCRLFPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6161916 | 0.99 | P2RY12 (0.51) | P2RY12CALCRLFPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6161920 | 0.99 | P2RY12 (0.51) | P2RY12CALCRLFPR2MEN1KMT2A | |
| SCHEMBL6163760 | 0.91 | CALCRL (0.54) | P2RY12CALCRLFPR2MEN1KMT2A | |
| SCHEMBL6163764 | 0.91 | CALCRL (0.54) | P2RY12CALCRLFPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6163197 | 0.91 | CALCRL (0.54) | P2RY12CALCRLFPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6163192 | 0.91 | CALCRL (0.54) | P2RY12CALCRLFPR2MEN1KMT2A | |
| SCHEMBL6164342 | 0.89 | MEN1 (0.50) | P2RY12CALCRLFPR2MEN1KMT2A | |
| SCHEMBL6164336 | 0.89 | MEN1 (0.50) | P2RY12CALCRLFPR2MEN1KMT2A | |
| SCHEMBL6165907 | 0.85 | MEN1 (0.51) | P2RY12CALCRLFPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |