Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 17/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.68 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409743 | 0.90 | CALCRL (0.67) | CALCRLCYP3A4 | |
| SCHEMBL6160376 | 0.89 | CALCRL (0.66) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6160383 | 0.89 | CALCRL (0.66) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6166567 | 0.88 | CALCRL (0.77) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6165522 | 0.88 | CALCRL (0.68) | CALCRLCYP3A4 | |
| SCHEMBL6165527 | 0.88 | CALCRL (0.68) | CALCRLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6162320 | 0.87 | CALCRL (0.76) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6162588 | 0.86 | CALCRL (0.51) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6162595 | 0.86 | CALCRL (0.51) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6168909 | 0.85 | CALCRL (0.65) | CALCRLCYP3A4RAMP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |