Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014816 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL1146057 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL7363076 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL5100760 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL5650522 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6638580 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL13649701 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL6657510 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL8365566 | 0.81 | DPP4 (0.58) | SMN1; SMN2POLBMAPTRAB9ANPC1 | |
| SCHEMBL5099213 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939632-B1 | NON-PEPTIDYL VASOPRESSIN V1a ANTAGONISTS | LILLY CO ELI (US) | 2005-10-05 | — | — | EP | disclosed |