Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 15/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162394 | 1.00 | CALCRL (0.67) | CALCRLCYP3A4MEN1KMT2ACCR5 | |
| SCHEMBL8409714 | 0.90 | CALCRL (0.67) | CALCRLCYP3A4MEN1KMT2ACCR5 | |
| SCHEMBL6161756 | 0.90 | CALCRL (0.67) | CALCRLCYP3A4MEN1KMT2ACCR5 | |
| SCHEMBL6163334 | 0.87 | CALCRL (0.67) | CALCRLCYP3A4CCR5CHRM2CHRM4 | |
| SCHEMBL6163332 | 0.87 | CALCRL (0.67) | CALCRLCYP3A4CCR5CHRM2CHRM4 | |
| SCHEMBL6160383 | 0.86 | CALCRL (0.66) | CALCRLCYP3A4 | |
| SCHEMBL6160376 | 0.86 | CALCRL (0.66) | CALCRLCYP3A4 | |
| SCHEMBL6164327 | 0.85 | CALCRL (0.75) | CALCRLCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL6163517 | 0.81 | CALCRL (0.69) | CALCRLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6169242 | 0.80 | CALCRL (0.70) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |