Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.41 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163317 | 0.97 | MAPT (0.56) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6161520 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6163170 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6161808 | 0.91 | MAPT (0.49) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6162773 | 0.90 | MAPT (0.48) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6165221 | 0.90 | MAPT (0.48) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6166175 | 0.89 | MAPT (0.47) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6162543 | 0.89 | MAPT (0.47) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6164180 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMAPK1NPC1LMNA | |
| SCHEMBL6164246 | 0.88 | MAPT (0.46) | SMN1; SMN2MAPTMAPK1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |