SCHEMBL6162843

SCHEMBL6162843

Cn1cncc1C(N)(c1ccc(Cl)cc1)c1cccc2c(-c3cccc(Cl)c3)cc(=O)n(CC3CC3)c12

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 17/20 0.59
FNTB P49356 17/20 0.59
PGGT1B P53609 3/20 0.59
CYP3A4 P08684 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6169078 0.93 FNTA (0.51) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6171460 0.90 FNTA (0.49) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6167630 0.90 FNTA (0.62) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6162839 0.87 FNTA (0.63) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5071351 0.86 FNTA (0.64) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6169238 0.84 FNTA (0.53) FNTAFNTBPGGT1B
SCHEMBL13177990 0.81 FNTA (0.54) FNTAFNTBPGGT1BCYP3A4
SCHEMBL3498778 0.80 FNTA (0.56) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6162996 0.80 FNTA (0.62) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5722593 0.80 CYP3A4 (0.57) FNTAFNTBPGGT1BCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107962-B1 QUINOLIN-2-ONE DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER PROD INC (US) 2005-02-23 EP claimed