SCHEMBL6162927

SCHEMBL6162927

CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC(C(=O)NCCCCO)(c2ccccc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CTSL P07711 2/20 0.46
CTSS P25774 1/20 0.46
CTSK P43235 1/20 0.46
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
ACHE P22303 2/20 0.45
UGCG Q16739 2/20 0.43
CYP3A4 P08684 1/20 0.43
BCHE P06276 1/20 0.42
PKM P14618 1/20 0.42
TACR1 P25103 1/20 0.42
ACE P12821 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162931 1.00 MEN1 (0.46) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6159567 0.91 MEN1 (0.51) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6159569 0.91 MEN1 (0.51) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161792 0.89 MEN1 (0.52) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161784 0.89 MEN1 (0.52) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6162144 0.87 MEN1 (0.49) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6159988 0.87 MEN1 (0.51) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6159981 0.87 MEN1 (0.51) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6160698 0.85 MEN1 (0.49) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6160703 0.85 MEN1 (0.49) MEN1KMT2ACTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP disclosed