Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6165952 | 0.94 | SMN1; SMN2 (0.46) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6166475 | 0.84 | SMN1; SMN2 (0.53) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6161730 | 0.84 | MAPT (0.49) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6168271 | 0.84 | SMN1; SMN2 (0.46) | F10MAPTMAPK1SMN1; SMN2F2 | |
| SCHEMBL6165871 | 0.83 | MAPT (0.48) | MAPTMAPK1SMN1; SMN2NPC1LMNA | |
| Trifluoroacetic Acid SCHEMBL6162234 | 0.81 | SMN1; SMN2 (0.48) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6161633 | 0.80 | F10 (0.46) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6163464 | 0.80 | SMN1; SMN2 (0.47) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6163059 | 0.80 | SMN1; SMN2 (0.47) | F10MAPTMAPK1SMN1; SMN2F2 | |
| Trifluoroacetic Acid SCHEMBL6166105 | 0.78 | SMN1; SMN2 (0.46) | F10MAPTMAPK1SMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |