Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 19/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 17/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 17/20 | 0.49 |
| ▸ | F10 | P00742 | 9/20 | 0.49 |
| ▸ | F2 | P00734 | 16/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6165958 | 0.82 | PRSS1 (0.46) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL7100400 | 0.80 | PRSS1 (0.49) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL7101536 | 0.77 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6165345 | 0.76 | F10 (0.54) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6162940 | 0.75 | F10 (0.59) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6166404 | 0.74 | PRSS1 (0.53) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6163954 | 0.71 | F10 (0.83) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6163788 | 0.70 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6165803 | 0.69 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6164650 | 0.68 | F10 (0.59) | PRSS1PRSS2PRSS3F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |