Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 16/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.60 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163599 | 1.00 | CALCRL (0.75) | CALCRLCYP3A4RAMP1GHSROPRM1 | |
| SCHEMBL6164023 | 0.92 | CALCRL (0.64) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL6163107 | 0.92 | CALCRL (0.64) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL6159881 | 0.92 | CALCRL (0.64) | CALCRLCYP3A4 | |
| SCHEMBL6159873 | 0.92 | CALCRL (0.64) | CALCRLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6161084 | 0.91 | CALCRL (0.63) | CALCRLCYP3A4GHSROPRM1 | |
| Hydrochloric Acid SCHEMBL6162625 | 0.91 | CALCRL (0.63) | CALCRLCYP3A4RAMP1 | |
| Hydrochloric Acid SCHEMBL6161566 | 0.91 | CALCRL (0.63) | CALCRLCYP3A4RAMP1 | |
| Hydrochloric Acid SCHEMBL6161092 | 0.91 | CALCRL (0.63) | CALCRLCYP3A4GHSROPRM1 | |
| SCHEMBL6164090 | 0.89 | CALCRL (0.60) | CALCRLCYP3A4GHSROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| CN-1143647-A | Dipeptides which promote release of growth hormone | PFIZER (US) | 1997-02-26 | — | — | CN | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |