Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 12/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6166475 | 0.91 | SMN1; SMN2 (0.53) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6166105 | 0.90 | SMN1; SMN2 (0.46) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6161730 | 0.89 | MAPT (0.49) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6162234 | 0.87 | SMN1; SMN2 (0.48) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6164880 | 0.87 | F2 (0.41) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6165807 | 0.87 | F2 (0.41) | PRSS1PRSS2PRSS3F10F2 | |
| Trifluoroacetic Acid SCHEMBL6163464 | 0.86 | SMN1; SMN2 (0.47) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6166227 | 0.86 | SMN1; SMN2 (0.40) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6163059 | 0.85 | SMN1; SMN2 (0.47) | PRSS1PRSS2PRSS3F10SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6166062 | 0.84 | SMN1; SMN2 (0.44) | PRSS1F10SMN1; SMN2F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |