Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 16/20 | 0.42 |
| ▸ | FEN1 | P39748 | 16/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164560 | 0.95 | ALOX5AP (0.45) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6166679 | 0.93 | CSNK1E (0.41) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6166689 | 0.87 | CSNK1E (0.41) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6165046 | 0.86 | ALOX5AP (0.42) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6164550 | 0.85 | ALOX5AP (0.46) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6166685 | 0.78 | CSNK1E (0.40) | CSNK1ECSNK1DALOX5APFEN1 | |
| SCHEMBL6166620 | 0.76 | ALOX5AP (0.44) | CSNK1EALOX5APFEN1PTGES2 | |
| SCHEMBL6164549 | 0.76 | F10 (0.56) | ALOX5APFEN1NAMPT | |
| SCHEMBL7389491 | 0.75 | F10 (0.45) | ALOX5APFEN1NAMPT | |
| SCHEMBL6166400 | 0.71 | ALOX5AP (0.47) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |