Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861000 | 0.88 | PPARD (0.54) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5860763 | 0.87 | SMN1; SMN2 (0.42) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5861731 | 0.85 | PPARD (0.62) | PPARDPPARAFFAR1 | |
| SCHEMBL5860755 | 0.85 | PTGDR2 (0.48) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5862790 | 0.84 | PPARD (0.46) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5861691 | 0.80 | PPARD (0.48) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5860613 | 0.80 | PPARD (0.49) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5862807 | 0.77 | SMN1; SMN2 (0.50) | PPARDPPARAPTGDR2PPARGSMN1; SMN2 | |
| SCHEMBL5860715 | 0.77 | PPARD (0.51) | PPARDPPARAPTGDR2 | |
| SCHEMBL5861915 | 0.73 | PPARD (0.56) | PPARDPPARAPTGDR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |