Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496895 | 0.88 | SLC18A3 (0.61) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL5666500 | 0.85 | CYP3A4 (0.43) | HTR1ACYP3A4SLC5A1SLC5A2 | |
| SCHEMBL3045406 | 0.84 | HTR2C (0.51) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL378006 | 0.77 | HTR2C (0.62) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL4518387 | 0.76 | HTR2C (0.62) | HTR2CSLC6A2SLC6A4SLC18A3SIGMAR1 | |
| SCHEMBL4404411 | 0.76 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1CYP3A4HTR6 | |
| SCHEMBL22567480 | 0.76 | HTR2C (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL7624146 | 0.76 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1CYP3A4SLC5A1 | |
| Hydrochloric Acid SCHEMBL1765281 | 0.76 | HTR2C (0.64) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL14282659 | 0.76 | SLC18A3 (0.68) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |