Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862763 | 0.91 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL5861814 | 0.87 | PPARD (0.50) | PPARDPPARGPPARA | |
| SCHEMBL6164372 | 0.85 | PPARA (0.39) | PPARDPPARGPPARA | |
| SCHEMBL5861924 | 0.83 | PPARD (0.58) | PPARDPPARGPPARA | |
| SCHEMBL5861093 | 0.82 | PPARD (0.66) | PPARDPPARA | |
| SCHEMBL5861723 | 0.80 | PPARD (0.66) | PPARDPPARGPPARA | |
| SCHEMBL5861741 | 0.79 | PPARD (0.41) | PPARDPPARGPPARA | |
| SCHEMBL5860732 | 0.78 | PPARD (0.51) | PPARDPPARGPPARA | |
| SCHEMBL5860821 | 0.78 | FFAR4 (0.54) | PPARDPPARGPPARA | |
| SCHEMBL5860796 | 0.76 | PPARD (0.67) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |