Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861174 | 0.84 | SMN1; SMN2 (0.44) | PPARDPPARGPPARA | |
| SCHEMBL6165846 | 0.78 | PPARD (0.60) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL3385737 | 0.73 | PPARD (0.69) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL5860635 | 0.71 | PPARD (0.68) | PPARD | |
| SCHEMBL5862762 | 0.71 | PPARD (0.72) | PPARDPPARAFFAR1 | |
| SCHEMBL28995198 | 0.70 | PPARD (0.63) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL5860589 | 0.70 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL5861786 | 0.69 | PPARD (0.57) | PPARDPPARA | |
| SCHEMBL5860892 | 0.69 | PPARD (0.61) | PPARDPPARGPPARA | |
| SCHEMBL13801358 | 0.68 | PPARD (0.86) | PPARDPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |