Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907317 | 0.83 | TACR1 (0.39) | TACR1SLC6A4KCNH2S1PR2BCHE | |
| SCHEMBL17164344 | 0.81 | TACR1 (0.38) | TACR1SLC6A4KCNH2S1PR2BCHE | |
| SCHEMBL6968674 | 0.80 | TACR1 (0.36) | TACR1SLC6A4KCNH2S1PR2IDO1 | |
| SCHEMBL1715959 | 0.80 | IDO1 (0.60) | IDO1CYP3A4 | |
| SCHEMBL2419315 | 0.80 | TACR1 (0.36) | TACR1SLC6A4KCNH2S1PR2IDO1 | |
| Hydrochloric Acid SCHEMBL1715092 | 0.78 | IDO1 (0.61) | IDO1CYP3A4 | |
| SCHEMBL6164307 | 0.78 | TACR1 (0.37) | TACR1SLC6A4KCNH2GRM5 | |
| SCHEMBL15431121 | 0.75 | GRM5 (0.35) | TACR1SLC6A4KCNH2S1PR2TSHR | |
| SCHEMBL5544170 | 0.75 | S1PR2 (0.36) | TACR1SLC6A4KCNH2S1PR2IDO1 | |
| SCHEMBL18213810 | 0.75 | TACR1 (0.34) | TACR1SLC6A4KCNH2S1PR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016661-B1 | 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AS AGRICULTURAL CHEMICALS | DAINIPPON INK & CHEMICALS (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6281231-B1 | 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals | DAINIPPON INK AND CHEMICAL, INC. (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-1016661-A1 | 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AND AGRICULTURAL CHEMICALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-07-05 | — | — | EP | disclosed |