Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165278 | 0.86 | PPARD (0.46) | PPARDPPARAPPARGPRMT1 | |
| SCHEMBL6165395 | 0.84 | PPARD (0.47) | PPARDPPARAPPARGAR | |
| SCHEMBL6167079 | 0.83 | PPARD (0.45) | PPARDPPARAPPARGAR | |
| SCHEMBL5860868 | 0.81 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL8192106 | 0.80 | PPARD (0.56) | PPARDPPARAPPARGAR | |
| SCHEMBL13224731 | 0.80 | PPARD (0.69) | PPARDPPARAPPARG | |
| SCHEMBL5860745 | 0.79 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL6167419 | 0.78 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL6167231 | 0.78 | PPARD (0.47) | PPARDPPARAPPARGAR | |
| SCHEMBL6163713 | 0.78 | PPARD (0.44) | PPARDPPARAPPARGAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |