Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.55 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.55 |
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6161743 | 0.84 | F2 (0.50) | F2TMPRSS6PLGF10 | |
| Trifluoroacetic Acid SCHEMBL6164542 | 0.82 | F2 (0.50) | F2TMPRSS6PLGF10PLAU | |
| Trifluoroacetic Acid SCHEMBL6165425 | 0.81 | CYP3A4 (0.45) | F2TMPRSS6CYP3A4CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7100339 | 0.80 | F10 (0.62) | F2TMPRSS6F10 | |
| Trifluoroacetic Acid SCHEMBL6166342 | 0.80 | F10 (0.56) | F2TMPRSS6F10 | |
| SCHEMBL16886887 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP2C19 | |
| SCHEMBL5313228 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP2C19 | |
| SCHEMBL16886884 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL6163326 | 0.79 | F10 (0.70) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL6167095 | 0.78 | F10 (0.54) | F2TMPRSS6F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |