Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860730 | 0.86 | CCR1 (0.41) | PPARD | |
| SCHEMBL5860757 | 0.82 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL5861109 | 0.82 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL5861953 | 0.80 | CCR1 (0.43) | — | |
| SCHEMBL5862762 | 0.79 | PPARD (0.72) | PPARDPPARA | |
| SCHEMBL5861715 | 0.79 | PPARD (0.73) | PPARDPPARAPPARG | |
| SCHEMBL4103423 | 0.79 | PPARD (0.54) | PPARDPPARAPPARG | |
| SCHEMBL5860831 | 0.78 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL5861802 | 0.77 | PPARD (0.61) | PPARDPPARA | |
| SCHEMBL5861949 | 0.76 | PPARD (0.68) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1392674-A1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092590-A1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |