Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165730 | 1.00 | ATM (0.46) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL7989798 | 0.96 | ATM (0.47) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL6157710 | 0.96 | ATM (0.47) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL29039395 | 0.92 | SMN1; SMN2 (0.42) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL29039393 | 0.92 | SMN1; SMN2 (0.42) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL29039237 | 0.91 | SMN1; SMN2 (0.41) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL29039235 | 0.91 | SMN1; SMN2 (0.41) | ATMSMN1; SMN2HSD17B10NPC1OPRD1 | |
| SCHEMBL702497 | 0.88 | ATM (0.43) | ATMSMN1; SMN2HSD17B10OPRD1KDM1A | |
| SCHEMBL16551790 | 0.86 | ATM (0.47) | ATMSMN1; SMN2HSD17B10OPRD1ALDH1A1 | |
| SCHEMBL6921210 | 0.86 | ATM (0.47) | ATMSMN1; SMN2HSD17B10OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234802-A | Quinoline CGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-1129070-A4 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1129070-A1 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6228872-B1 | PEPTIDE-PROLYL ISOMERASE AND ROTAMASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2001-05-08 | — | — | US | disclosed |
| WO-2000027811-A1 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |