Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165822 | 1.00 | CALCRL (0.55) | CALCRLMEN1KMT2ACTSLCYP3A4 | |
| SCHEMBL8409743 | 0.90 | CALCRL (0.67) | CALCRLMEN1KMT2ACTSLCYP3A4 | |
| SCHEMBL6164093 | 0.89 | CALCRL (0.60) | CALCRLCYP3A4FPR2 | |
| SCHEMBL6164090 | 0.89 | CALCRL (0.60) | CALCRLCYP3A4FPR2 | |
| SCHEMBL6163303 | 0.89 | CALCRL (0.58) | CALCRLMEN1KMT2ACTSLCYP3A4 | |
| SCHEMBL6163308 | 0.89 | CALCRL (0.58) | CALCRLMEN1KMT2ACTSLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6163548 | 0.88 | CALCRL (0.57) | CALCRLMEN1KMT2ACTSLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6159774 | 0.88 | CALCRL (0.60) | CALCRLCYP3A4FPR2 | |
| Hydrochloric Acid SCHEMBL6159779 | 0.88 | CALCRL (0.60) | CALCRLCYP3A4FPR2 | |
| SCHEMBL6163594 | 0.88 | MEN1 (0.49) | CALCRLMEN1KMT2ACTSLSSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |