Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.75 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.75 |
| ▸ | GRK2 | P25098 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405312 | 0.86 | SCN4A (1.00) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL30320026 | 0.86 | SCN4A (1.00) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL6164077 | 0.86 | SCN4A (1.00) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL17067808 | 0.84 | SCN4A (0.57) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL6166125 | 0.83 | SCN4A (0.74) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL6165996 | 0.81 | SCN4A (0.76) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL1105594 | 0.81 | SCN4A (0.76) | SCN4ASCN9AKMT2ANPC1RAB9A | |
| SCHEMBL6164026 | 0.81 | SCN9A (0.63) | SCN4ASCN9AKMT2AALDH1A1MAPT | |
| SCHEMBL6165837 | 0.80 | SCN4A (0.74) | SCN4ASCN9AGRK2KMT2ANPC1 | |
| SCHEMBL6163679 | 0.80 | SCN4A (0.74) | SCN4ASCN9AKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986540-B1 | THE USE OF CARBOCYCLIC AND HETEROCYCLIC SUBSTITUTED SEMICARBAZONES AND THIOSEMICARBAZONES AS SODIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2005-02-16 | — | — | EP | claimed |