Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.53 |
| ▸ | F2 | P00734 | 14/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6164437 | 0.95 | F10 (0.51) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6167095 | 0.93 | F10 (0.54) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6164993 | 0.88 | F10 (0.54) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6163380 | 0.87 | F10 (0.52) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6174580 | 0.87 | F10 (0.52) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6164055 | 0.87 | F10 (0.51) | F10F2TMPRSS6PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6164228 | 0.86 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6167642 | 0.85 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6162344 | 0.85 | F9 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6162199 | 0.84 | F9 (0.47) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |