Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.46 |
| ▸ | PPARA | Q07869 | 13/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166728 | 0.88 | PPARD (0.47) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6166189 | 0.85 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL5862747 | 0.83 | PPARD (0.69) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL5862816 | 0.81 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL2166922 | 0.77 | PPARD (0.69) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL8192106 | 0.77 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL13780360 | 0.77 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5860969 | 0.75 | STK17B (0.40) | PPARDPPARASTK17BMEN1ALDH1A1 | |
| SCHEMBL4809153 | 0.75 | PPARD (0.56) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6758620 | 0.75 | PPARD (0.58) | PPARDPPARAPPARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |