Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.68 |
| ▸ | CNR1 | P21554 | 13/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483174 | 1.00 | CNR2 (0.68) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL11852714 | 0.81 | TOP2A (0.55) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL4717954 | 0.81 | KDM4E (0.63) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL29433778 | 0.81 | KDM4E (0.63) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL4717957 | 0.81 | KDM4E (0.63) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL11858118 | 0.81 | TOP2A (0.55) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL10330772 | 0.79 | TOP2A (0.59) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL11858912 | 0.79 | TOP2A (0.59) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL9144791 | 0.78 | TOP2A (0.58) | CNR2CNR1KDM4EKMT2ATOP2A | |
| SCHEMBL2080555 | 0.78 | TOP2A (0.66) | CNR2CNR1KDM4EKMT2ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134219-B1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6573260-B1 | Antibiotics | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1134219-A1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |