Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819522 | 0.79 | CYP2B6 (0.42) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| SCHEMBL9113434 | 0.79 | CYP2B6 (0.42) | CYP1A2CYP1A1CYP1B1CYP2B6 | |
| SCHEMBL6247638 | 0.79 | CYP2B6 (0.42) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| Biphenyl SCHEMBL27808086 | 0.77 | CYP1A1 (0.47) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| SCHEMBL9112587 | 0.76 | CYP2B6 (0.39) | CYP1A2CYP1A1CYP2B6KDM4EHPGD | |
| SCHEMBL29372595 | 0.71 | CYP2B6 (0.43) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| SCHEMBL1043402 | 0.71 | CYP2B6 (0.43) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| SCHEMBL29365059 | 0.71 | CYP2B6 (0.43) | CYP1A2CYP1A1CYP1B1CYP2B6KDM4E | |
| SCHEMBL3708936 | 0.71 | HPRT1 (0.47) | CYP1A2CYP1A1CYP1B1CYP2B6HPGD | |
| SCHEMBL9112001 | 0.70 | HTT (0.47) | CYP1A2CYP1A1CYP2B6KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304842-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| WO-2022189940-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | claimed |
| CN-102112528-B | Photochromic polymer and composition comprising photochromic polymer | ADVANCED POLYMERIK PTY LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-102112528-A | Photochromic polymer and composition comprising photochromic polymer | ADVANCED POLYMERIK PTY LTD | 2011-06-29 | — | — | CN | disclosed |
| EP-0792468-B2 | NOVEL PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 2005-05-04 | — | — | EP | disclosed |
| EP-0792468-B1 | NOVEL PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| CN-1168725-A | Novel photochromic indeno fused naphthopyrans | PPG INDUSTRIES INC (US) | 1997-12-24 | — | — | CN | disclosed |
| EP-0250193-B1 | Photoreactive lenses | MARCONI GEC LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-4818096-A | SUNGLASSES; BENZO OR NAPHTHOPYRANS WITH NITROGEN CONTAINING SUBSTITUENTS | THE PLESSEY COMPANY PLC (GB) | 1989-04-04 | — | — | US | disclosed |
| CN-87104827-A | The lens of light reaction | — | 1988-03-02 | — | — | CN | disclosed |
| EP-0250193-A2 | Photoreactive lenses | GEC-MARCONI LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |