Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CDC14B | O60729 | 1/20 | 0.30 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987754 | 0.78 | HTR2C (0.43) | HTR2CCDC14BCDC14A | |
| SCHEMBL31333134 | 0.74 | HTR2A (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL31553097 | 0.74 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL4995601 | 0.71 | IDO1 (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL5153438 | 0.71 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL15538116 | 0.69 | RXFP1 (0.42) | CDC14BCDC14A | |
| SCHEMBL26778135 | 0.69 | HTR2C (0.34) | HTR2C | |
| SCHEMBL31417703 | 0.67 | HTR2A (0.32) | HTR2CHTR2AHTR2B | |
| SCHEMBL6334685 | 0.67 | CYP1A2 (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL3596610 | 0.67 | HTR2A (0.32) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |