⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985399 | 0.94 | — | — | |
| SCHEMBL8392183 | 0.94 | — | — | |
| SCHEMBL428089 | 0.88 | — | — | |
| SCHEMBL615138 | 0.82 | — | — | |
| SCHEMBL550653 | 0.76 | — | — | |
| SCHEMBL184495 | 0.70 | — | — | |
| SCHEMBL15389499 | 0.70 | — | — | |
| SCHEMBL815726 | 0.67 | — | — | |
| SCHEMBL15654169 | 0.67 | — | — | |
| SCHEMBL9987289 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273582-B1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1273580-B1 | Sulfonyl heteroaryl triazoles as anti-inflammatory and analgesic agents | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6900230-B2 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-6875779-B2 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-04-05 | — | — | US | disclosed |
| EP-1233959-B1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20040198735-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2004-10-07 | — | — | US | disclosed |
| US-6753332-B2 | CYCLOOXYGENASE INHIBITORS | PFIZER, INC. | 2004-06-22 | — | — | US | disclosed |
| US-20030125368-A1 | Sulfonyl aryl triazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2003-07-03 | — | — | US | disclosed |
| US-20030119835-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER PRODUCTS, INC. | 2003-06-26 | — | — | US | disclosed |
| US-20030119836-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2003-06-26 | — | — | US | disclosed |
| US-6531492-B1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-03-11 | — | — | US | disclosed |
| EP-1273576-A1 | Sulfonyl aryl triazoles as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1273582-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1273580-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory and analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1233959-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | Pfizer Products Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040216-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |