Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221875 | 0.75 | DPP4 (0.48) | DPP4 | |
| SCHEMBL16540165 | 0.75 | MEN1 (0.38) | — | |
| SCHEMBL29752465 | 0.74 | DPP4 (0.65) | DPP4 | |
| SCHEMBL29752419 | 0.73 | DPP4 (0.53) | DPP4 | |
| SCHEMBL20329734 | 0.72 | DPP4 (0.57) | DPP4 | |
| SCHEMBL3393660 | 0.72 | DPP4 (0.57) | DPP4 | |
| SCHEMBL3786751 | 0.72 | DPP4 (0.57) | DPP4 | |
| SCHEMBL3787988 | 0.72 | DPP4 (0.57) | DPP4 | |
| SCHEMBL3398160 | 0.72 | DPP4 (0.57) | DPP4 | |
| SCHEMBL5221694 | 0.71 | DPP4 (0.48) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465891-A4 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARM INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1465891-A2 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057666-A2 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS (US) | 2003-07-17 | — | — | WO | disclosed |