Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 17/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.44 |
| ▸ | OXTR | P30559 | 5/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.44 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674083 | 0.89 | AVPR1B (0.42) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL6168441 | 0.89 | AVPR1B (0.48) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5675503 | 0.85 | AVPR1B (0.47) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL6167877 | 0.85 | AVPR1B (0.58) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5066029 | 0.84 | AVPR1B (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL6168124 | 0.82 | AVPR1B (0.44) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL6165507 | 0.81 | AVPR1B (0.54) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5674074 | 0.80 | AVPR1B (0.42) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL6167699 | 0.80 | AVPR1B (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5678001 | 0.79 | AVPR1B (0.48) | AVPR1BAVPR1AOXTRAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419150-B1 | PHENYLSULFONYL-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2005-04-27 | — | — | EP | disclosed |
| EP-1419150-A2 | PHENYLSULFONYL-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sanofi-Aventis (FR) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003008407-A2 | PHENYLSULFONYL-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |