Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169291 | 1.00 | SLC6A4 (0.41) | SLC6A4LMNAMAPK1PGR | |
| SCHEMBL468605 | 0.90 | SLC6A4 (0.39) | SLC6A4LMNAMAPK1PGR | |
| SCHEMBL468481 | 0.87 | SLC6A4 (0.42) | SLC6A4LMNAMAPK1PGR | |
| SCHEMBL3408122 | 0.86 | SLC6A4 (0.52) | SLC6A4LMNAMAPK1 | |
| SCHEMBL3408118 | 0.86 | SLC6A4 (0.52) | SLC6A4LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6167899 | 0.85 | SLC6A4 (0.51) | SLC6A4LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6167895 | 0.85 | SLC6A4 (0.51) | SLC6A4LMNAMAPK1 | |
| SCHEMBL3403018 | 0.81 | SLC6A4 (0.39) | SLC6A4PGR | |
| SCHEMBL21065409 | 0.75 | SLC6A4 (0.43) | SLC6A4LMNAMAPK1 | |
| SCHEMBL21065410 | 0.75 | SLC6A4 (0.43) | SLC6A4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921774-B2 | Compounds and their use as glycine transport inhibitors | H. LUNDBECK A/S (DK) | 2005-07-26 | — | — | US | disclosed |
| EP-1301502-B1 | COMPOUNDS AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | LUNDBECK & CO AS H (DK) | 2005-05-18 | — | — | EP | disclosed |
| US-20030181445-A1 | Novel compounds and their use as glycine transport inhibitors | H. LUNDBECK A/S (DK) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181445-A1 | Novel compounds and their use as glycine transport inhibitors | SLC1A5, SLC7A1, SLC7A11 | SLC6A4 75/4885LMNA 3636/4885MAPK1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.