Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629164 | 0.89 | PTGER1 (0.55) | PTGER1MAOBCYP2C9 | |
| SCHEMBL5627611 | 0.82 | PTGER1 (0.65) | PTGER1CYP2C9 | |
| SCHEMBL6168885 | 0.82 | PTGER1 (0.66) | PTGER1CYP2C9 | |
| SCHEMBL5629219 | 0.81 | PTGER1 (0.57) | PTGER1CYP2C9 | |
| SCHEMBL5629562 | 0.81 | PTGER1 (0.56) | PTGER1CYP2C9 | |
| SCHEMBL5628695 | 0.81 | PTGER1 (0.66) | PTGER1CYP2C9 | |
| SCHEMBL5630101 | 0.80 | PTGER1 (0.67) | PTGER1CYP2C9 | |
| SCHEMBL5628801 | 0.80 | PTGER1 (0.55) | PTGER1CYP2C9 | |
| SCHEMBL5627659 | 0.79 | PTGER1 (0.68) | PTGER1CYP2C9 | |
| SCHEMBL6170672 | 0.78 | PTGER1 (0.60) | PTGER1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101959-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |