Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617345 | 0.82 | KMT2A (0.47) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL13716846 | 0.82 | KMT2A (0.47) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL29439591 | 0.82 | KMT2A (0.47) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL628538 | 0.82 | KMT2A (0.47) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL4225491 | 0.82 | KMT2A (0.69) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL14864593 | 0.81 | MEN1 (0.53) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL6171056 | 0.81 | MEN1 (0.67) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL17034341 | 0.81 | KMT2A (0.46) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL12126827 | 0.80 | NPC1 (0.50) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL13716857 | 0.80 | KMT2A (0.45) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6914160-B1 | Oxytocin inhibitors | PFIZER INC (US) | 2005-07-05 | — | — | US | disclosed |
| EP-1537085-A1 | OXYTOCIN INHIBITORS | Pfizer Limited (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020414-A1 | OXYTOCIN INHIBITORS | PFIZER LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |