Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13520371 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL4458434 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL12119817 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL20745544 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL1552535 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL6474347 | 1.00 | CA1 (0.47) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL13864151 | 0.90 | CA1 (0.45) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL13864146 | 0.90 | CA1 (0.45) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL29323075 | 0.90 | CA1 (0.45) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL15604758 | 0.89 | CA1 (0.44) | CA1CA2CA7CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |