SCHEMBL6170281

SCHEMBL6170281

Cc1ccc(CCC(CO[Si](C)(C)C(C)(C)C)n2cnc(C(N)=O)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADA P00813 17/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6173086 0.84 ADA (0.78) ADA
SCHEMBL6171958 0.82 ADA (0.56) ADA
SCHEMBL6171955 0.82 ADA (0.56) ADA
SCHEMBL7669344 0.82 ADA (0.50) ADA
SCHEMBL7669799 0.82 ADA (0.52) ADA
SCHEMBL7451629 0.81 ADA (0.55) ADA
SCHEMBL7451634 0.81 ADA (0.55) ADA
SCHEMBL6170286 0.80 ADA (0.46) ADA
SCHEMBL6935383 0.79 ADA (0.81) ADA
SCHEMBL6935332 0.79 ADA (0.57) ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098885-B9 IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS FUJISAWA PHARMACEUTICAL CO (JP) 2005-05-18 EP disclosed
EP-1098885-B1 IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS FUJISAWA PHARMACEUTICAL CO (JP) 2004-11-17 EP disclosed
US-6359145-B1 ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-03-19 US disclosed