Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290933 | 0.87 | CA12 (0.53) | CA12CA1CA2CA9HTT | |
| SCHEMBL7415486 | 0.86 | CA12 (0.56) | CA12CA1CA2CA9HTT | |
| SCHEMBL27501720 | 0.85 | CA12 (0.55) | CA12CA1CA2CA9HTT | |
| SCHEMBL8671692 | 0.84 | CA12 (0.50) | CA12CA1CA2CA9HTT | |
| SCHEMBL25400902 | 0.84 | CA12 (0.51) | CA12CA1CA2CA9HTT | |
| SCHEMBL27346972 | 0.83 | CA12 (0.59) | CA12CA1CA2CA9HTT | |
| SCHEMBL27440468 | 0.83 | CA12 (0.50) | CA12CA1CA2CA9HTT | |
| SCHEMBL5267117 | 0.83 | CA12 (0.50) | CA12CA1CA2CA9HTT | |
| SCHEMBL1291104 | 0.83 | CA12 (0.46) | CA12CA1CA2CA9HTT | |
| SCHEMBL25399615 | 0.82 | MEN1 (0.51) | CA12CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534693-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004022523-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | claimed |